Scientists from the Washington University School of Medicine in St. Louis (USA) have discovered an antibody that can neutralize all known coronavirus mutations. The study was published on the official portal of the university.
The authors studied 43 samples and analyzed how they prevent infection with the initial variant of SARS-CoV-2 in a Petri dish. Then nine of the most powerful neutralizing particles were tested on rodents, after which the most effective ones were selected.
It turned out that SARS2-38 can fight common variants of the coronavirus – alpha, beta, gamma, delta, kappa, iota — as well as rare mutations. According to scientists, SARS2-38 attaches to the part of the virus’s spike protein that remains unchanged. Among the unique properties of the detected antibody is a high ability to neutralize at a low concentration and the effect on all variants of the pathogen of infection.
Since there is a risk of new mutations in the future, effective neutralizing antibodies are needed that can support the body’s immunity both independently, and in combination with therapy, the researchers concluded.