Puria Lesani, PhD in biology at the University of Sydney, has developed a biomedical probe for cancer detection from rancid orange juice.
The size of the nanobiosensor is one billionth of a meter. It was made from fluorescent carbon dots from rotten orange juice. Spoiled oranges are high in ascorbic acid. The scientists added rancid orange juice and some water to a pressure cooker-like reactor and heated it to 200 ° C. The increased temperature and pressure inside the reactor destroyed the original molecular structure of the ingredients and helped them form a new material: carbon dots. These points were used to create a nanobiosensor.
The process of examining cancer cells involves taking a biopsy of tissue cells, presumably cancerous, which are placed in a Petri dish. Using a laboratory pipette, the nanobiosensor was applied to the cells. They then examined them under a fluorescence microscope, which shows subtle changes in light.
A biologist has used fluorescence to determine the pH of cells in terms of acidity or alkalinity. When acidity rises in human cells, it may indicate signs of cancer. This method can determine the early stages of cancer and other serious diseases.
“Many diseases develop over the years before a person shows even the slightest symptoms. In many diseases, it is too late to treat the symptoms that have appeared, ”said Dr. Lesani. “Our device accurately diagnoses diseases and detects them at an early stage.”
Modern testing methods are complex, expensive and time consuming, while the nanobiosensor is easy to manufacture on a large scale at low cost.