The first major mutation found in the genome of coronavirus

Singaporean biologists have discovered the first major change in the genome of the coronavirus SARS-CoV-2. A study by biologists and doctors from Singapore National University is published in an article for the bioRxiv electronic scientific library.

Compared to the first samples of the new coronavirus, a 382-letter-long nucleotide fragment disappeared from its genome next to ORF8, a special site in the coronavirus RNA that is responsible for starting the process of assembling protein N, one of the key components of SARS-CoV-2. It is this fragment of coronavirus that is associated with the copying of its RNA and the formation of new viral particles.

Scientists believe that the coronavirus mutation occurred in February 2020. A change in the genome made it less active in the first phases of infection and, accordingly, less noticeable for human immunity.

Such a change allowed the coronavirus to increase the speed of spread even in the conditions of struggle with it. In addition, a gene mutation has led to the fact that the symptoms of a new type of coronavirus infection appear up to 14 days after infection.

At the same time, scientists previously believed that SARS-CoV-2 is stable and cannot mutate in response to external factors. Biologists and physicians from Singapore National University have come to a new conclusion by studying coronavirus samples from the secretions that were collected from all patients in Singapore clinics.

If you have found a spelling error, please, notify us by selecting that text and pressing Ctrl+Enter.

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Author: Ivan Maltsev
The study of political and social problems of different countries of the world. Analysis of large companies on the world market. Observing world leaders in the political arena.
Function: Chief-Editor
Ivan Maltsev

Spelling error report

The following text will be sent to our editors: